We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
Read More
9
Zinc reduces postoperative sore throat
The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study.
We explored the potential benefits of zinc lozenges for easing postoperative sore throat (POST), a common discomfort following endotracheal intubation. By conducting a randomized, double-blinded trial with 79 patients undergoing low- to moderate-risk surgeries, we divided participants into two groups: one received zinc lozenges, while the other was given a placebo.
Our findings revealed promising results. At the crucial four-hour mark post-surgery, only 7% of patients who took zinc experienced POST, compared to 29% in the placebo group. Interestingly, the difference was even more pronounced right after surgery, where the zinc group reported a 0% incidence of POST versus 24% for the control group.
Moreover, the severity of sore throat symptoms was notably less intense among those in the zinc group. Those with mild and moderate sore throat pains reported significantly lower severity scores. These results suggest that a single dose of 40 mg of zinc lozenges taken just 30 minutes before surgery can greatly aid in reducing both the occurrence and discomfort of POST in the early hours after surgery.
Read More
9.5
Zinc reduces postoperative sore throat
A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation.
We conducted a study to understand how well zinc can help prevent postoperative sore throat (POST) after endotracheal intubation. We compared the effects of gargling with zinc sulphate versus magnesium sulphate in a controlled trial involving 132 patients. Those in the zinc group received a solution with 40 mg of elemental zinc, while the magnesium group used 20 mg/kg of magnesium sulphate, with a control group receiving only dextrose.
Our findings showed that the group using zinc sulphate experienced notably lower rates of sore throat compared to those using magnesium sulphate. Specifically, the incidence of mild POST was significantly lower in the zinc group, especially during the first four hours after surgery. Overall, zinc gargle proved to be more effective in reducing sore throat compared to magnesium sulphate, demonstrating its potential benefits in postoperative care.
These results highlight the importance of zinc as a simple yet effective intervention to reduce discomfort for patients following surgery. By using zinc gargle preoperatively, we can potentially improve patient outcomes related to postoperative sore throat.
Read More
Most Useful Reviews
9
Prevents illness
At the first signs of a cold or sore throat, I combine it with vitamin C from ESTER-C. It prevents me from getting sick, and after a few days, I feel fantastic.
Read More
9
Rapid relief noted
An excellent zinc supplement I always keep in stock. At the first signs of a sore throat and nasal congestion, I take two capsules with vitamin D and C. After two days, signs of a cold vanish completely.
Read More
9
Quick remedy verified
After receiving the zinc, I began to feel unwell. With the first signs of a sore throat and runny nose, I took one capsule a day and didn’t fall sick; within two days, all symptoms vanished.
A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation.
We conducted a study to understand how well zinc can help prevent postoperative sore throat (POST) after endotracheal intubation. We compared the effects of gargling with zinc sulphate versus magnesium sulphate in a controlled trial involving 132 patients. Those in the zinc group received a solution with 40 mg of elemental zinc, while the magnesium group used 20 mg/kg of magnesium sulphate, with a control group receiving only dextrose.
Our findings showed that the group using zinc sulphate experienced notably lower rates of sore throat compared to those using magnesium sulphate. Specifically, the incidence of mild POST was significantly lower in the zinc group, especially during the first four hours after surgery. Overall, zinc gargle proved to be more effective in reducing sore throat compared to magnesium sulphate, demonstrating its potential benefits in postoperative care.
These results highlight the importance of zinc as a simple yet effective intervention to reduce discomfort for patients following surgery. By using zinc gargle preoperatively, we can potentially improve patient outcomes related to postoperative sore throat.
Read More
9.5
Zinc reduces postoperative sore throat
Preoperative oral zinc tablet decreases incidence of postoperative sore throat.
We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
Read More
9
Zinc reduces postoperative sore throat
The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study.
We explored the potential benefits of zinc lozenges for easing postoperative sore throat (POST), a common discomfort following endotracheal intubation. By conducting a randomized, double-blinded trial with 79 patients undergoing low- to moderate-risk surgeries, we divided participants into two groups: one received zinc lozenges, while the other was given a placebo.
Our findings revealed promising results. At the crucial four-hour mark post-surgery, only 7% of patients who took zinc experienced POST, compared to 29% in the placebo group. Interestingly, the difference was even more pronounced right after surgery, where the zinc group reported a 0% incidence of POST versus 24% for the control group.
Moreover, the severity of sore throat symptoms was notably less intense among those in the zinc group. Those with mild and moderate sore throat pains reported significantly lower severity scores. These results suggest that a single dose of 40 mg of zinc lozenges taken just 30 minutes before surgery can greatly aid in reducing both the occurrence and discomfort of POST in the early hours after surgery.
Read More
8
Zinc's role in sore throat treatment
The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial.
We evaluated a promising dietary supplement that combines honey, propolis, and zinc to see how effective it could be for children suffering from acute tonsillopharyngitis, a type of sore throat. In this open-label, randomized, and controlled study, we compared the supplement along with standard care against standard care alone over six days.
The results revealed that incorporating the supplement with standard care led to notable improvements in certain symptoms associated with sore throat, such as throat pain and swallowing difficulties by day four and six. Although zinc was part of the blend, it was challenging to pinpoint its independent effect, given that it was studied alongside honey and propolis.
Interestingly, only one child in the standard care group needed additional medications like ibuprofen, highlighting that the supplement may reduce the need for further treatment. Importantly, we did not report any adverse events, making this combination a potential safe addition to treatment.
Overall, while the study presents encouraging results regarding the adjunctive use of the supplement in treating sore throat, it remains unclear how much zinc alone contributes to its effectiveness.
Read More
8
Zinc's variable effectiveness for sore throat
Zinc deficits, mucositis, and mucosal macrophage perturbation: is there a relationship?
We examined recent findings regarding zinc's impact on sore throat, particularly in post-operative settings. Some studies have reported that specific zinc formulations, like polaprezinc, can effectively reduce symptoms associated with sore throat after procedures like endotracheal intubation.
Importantly, zinc sulfate showed mixed results, with one review suggesting it did not significantly decrease the occurrence or intensity of oral mucositis in cancer patients. However, there are indications that certain zinc preparations may still hold promise in specific contexts, such as managing sore throat post-surgery.
Overall, while zinc's benefits in sore throat treatment appear to vary, ongoing research explores the best applications and formulations of zinc to potentially ease discomfort. As such, individuals seeking relief should keep an eye on emerging studies that could clarify zinc's role in throat health.
At the first signs of a cold or sore throat, I combine it with vitamin C from ESTER-C. It prevents me from getting sick, and after a few days, I feel fantastic.
Read More
9
Rapid relief noted
An excellent zinc supplement I always keep in stock. At the first signs of a sore throat and nasal congestion, I take two capsules with vitamin D and C. After two days, signs of a cold vanish completely.
Read More
9
Quick remedy verified
After receiving the zinc, I began to feel unwell. With the first signs of a sore throat and runny nose, I took one capsule a day and didn’t fall sick; within two days, all symptoms vanished.
Read More
9
Effective for kids
A remarkable product for when one starts to feel unwell. I tested it on my daughter, and it works! The following day after taking zinc for sore throat symptoms, they disappear completely, so we continue for an additional three days.
Read More
7.5
Effective for symptoms
I take the tablet at the first symptoms of a cold, flu, or sore throat. It helps and tastes pleasant.
A sore throat, also known as pharyngitis, is a common condition characterized by pain, scratchiness, or irritation of the throat. It can occur as a result of various factors, including viral infections like the common cold or flu, bacterial infections such as strep throat, allergies, dry air, or even irritants like smoke and pollution. Symptoms often manifest as a sensation of discomfort during swallowing and may be accompanied by swelling, redness, or the presence of white patches on the tonsils or throat lining.
Most sore throats are mild and resolve on their own within a week or so, often treated with home remedies such as warm salt water gargles, lozenges, and hydration. However, if the sore throat is severe, persistent, or associated with other concerning symptoms such as high fever, difficulty swallowing, or difficulty breathing, it's essential to consult a healthcare professional, as this may indicate a more serious condition that requires medical intervention. Proper diagnosis and treatment are crucial, especially if a bacterial infection is suspected, as it may necessitate antibiotics for effective treatment.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential effects on the immune system, and some evidence suggests it may help alleviate sore throat symptoms. Particularly, zinc lozenges or syrups may shorten the duration of a sore throat when taken at the onset of symptoms. The reasoning behind this is that zinc can inhibit the replication of the virus responsible for the cold and boost immune response, thus potentially providing some relief.
However, it’s important to use zinc cautiously, as high doses can lead to side effects such as nausea or a bad taste in the mouth. Most health experts recommend opting for zinc in moderate doses, ideally through lozenges, which can also provide some soothing effects. While zinc might not be a cure-all, it can be a helpful part of a broader treatment plan that includes rest, hydration, and over-the-counter pain relievers. If your sore throat persists or is accompanied by other severe symptoms, consulting with a healthcare professional is advisable.
Based on user reviews, individuals typically report seeing results within two days of starting this zinc supplement for sore throat relief. For instance, one user noted that after taking the supplement at the first signs of a sore throat, all symptoms vanished completely within two days Read Review. Similarly, another reviewer mentioned that following the onset of a sore throat, they took one capsule daily and found that their symptoms disappeared by the end of the second day Read Review.
Others echoed similar sentiments, with reports of sore throat symptoms disappearing by the following day after beginning the supplementation Read Review. This consistent feedback suggests that those using this supplement can generally expect relief from sore throat symptoms within a span of one to two days when taken promptly at the onset of discomfort.
Scientific research offers promising insights into the potential benefits of zinc combined with other ingredients for treating sore throat, particularly in children. A study observed that a supplement containing honey, propolis, and zinc improved symptoms of sore throat and reduced the need for additional medications when used alongside standard care. However, the specific contribution of zinc to these benefits remains unclear, as it was evaluated in conjunction with other components ([1]). Another research highlighted the effectiveness of zinc in alleviating throat pain symptoms in acute cases, although isolating its impact from other elements in the supplement proved challenging ([2]).
In postoperative contexts, zinc has shown effectiveness in reducing sore throat incidence. Two separate studies found that patients receiving zinc before and after intubation experienced significantly lower rates of postoperative sore throat compared to those on placebo treatments ([5], [7]). While some studies indicate zinc's potential efficacy in various formulations, ongoing research is still needed to determine its definitive role in sore throat management. Overall, if you are considering a zinc supplement for sore throat relief, the existing evidence suggests it might be beneficial, especially when combined with other soothing ingredients.
Based on user reviews, many individuals have reported significant improvements in their symptoms when using this zinc supplement. Users commonly indicate that taking the supplement at the early signs of a sore throat or cold can lead to rapid relief. For example, one user mentioned that by combining it with vitamin C, they were able to prevent getting sick and felt fantastic within days Read Review. Another reviewer highlighted that after taking two capsules along with vitamin D and C, their cold symptoms completely vanished after two days Read Review.
Anecdotal evidence suggests that many users experience relief from sore throat symptoms by the following day after starting the supplement; one parent noted that their daughter's symptoms disappeared entirely after just one day of use Read Review. Other reviews also commend the supplement for its effectiveness in alleviating throat discomfort Read Review and preventing the progression of cold symptoms Read Review. As always, individual results can vary, but the overall feedback indicates a strong potential for symptom improvement when using this supplement promptly.
Users report favorable outcomes when combining zinc supplements with other vitamins, particularly vitamin C and D, for dealing with sore throat symptoms. For instance, one reviewer indicated that at the first signs of a sore throat, they take zinc along with vitamin C, which prevents them from getting sick, leading to a feeling of well-being within a few days Read Review. Another user mentioned that taking zinc with both vitamin C and D results in a complete resolution of their cold symptoms within two days Read Review.
The consensus among users suggests that these combinations enhance the overall effectiveness of the zinc supplement in alleviating throat discomfort and other cold symptoms. Furthermore, anecdotal experiences indicate that incorporating these vitamins can lead to quicker symptom relief, with one parent confirming that their child's sore throat symptoms disappeared entirely after just one day of taking zinc Read Review. Overall, combining zinc with vitamin C and D appears to provide substantial support for managing sore throat symptoms.
Users report a variety of dosages for zinc when treating sore throat symptoms, with many suggesting an approach that incorporates complementary vitamins. Several reviewers indicate taking two capsules at the onset of symptoms, stating it effectively alleviated their discomfort in a matter of days (Read Review). Meanwhile, another user mentions taking one capsule daily and experiencing symptom relief within 48 hours (Read Review).
Additionally, a few users highlighted taking zinc lozenges every two hours during their sore throat episodes, which they found to be particularly soothing (Read Review). This suggests that both dosage frequency and the combination with other vitamins, such as Vitamin C and D, might play a significant role in the effectiveness of zinc for treating sore throat symptoms. Overall, while specific dosage recommendations varied, users emphasized the importance of starting zinc supplementation at the first signs of illness for optimal results.
9
Rapid relief noted
An excellent zinc supplement I always keep in stock. At the first signs of a sore throat and nasal congestion, I take two capsules with vitamin D and C. After two days, signs of a cold vanish completely.
9
Quick remedy verified
After receiving the zinc, I began to feel unwell. With the first signs of a sore throat and runny nose, I took one capsule a day and didn’t fall sick; within two days, all symptoms vanished.
9
Effective for kids
A remarkable product for when one starts to feel unwell. I tested it on my daughter, and it works! The following day after taking zinc for sore throat symptoms, they disappear completely, so we continue for an additional three days.
9
Prevents illness
At the first signs of a cold or sore throat, I combine it with vitamin C from ESTER-C. It prevents me from getting sick, and after a few days, I feel fantastic.
7.5
Taste and effectiveness
I consistently take zinc, with a pleasant taste that soothes the throat when resorbed. I took these lozenges every two hours during a sore throat, which greatly alleviated my discomfort. I recommend taking it not on an empty stomach.
6
Boosts immune response
High-quality product that helps prevent the growth of pathogens in the throat and upper respiratory tract, speeding up recovery from colds and sore throat. Zinc glycinate is well-absorbed, and pumpkin seed oil aids zinc absorption.
8
Zinc's role in sore throat treatment
The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial.
We evaluated a promising dietary supplement that combines honey, propolis, and zinc to see how effective it could be for children suffering from acute tonsillopharyngitis, a type of sore throat. In this open-label, randomized, and controlled study, we compared the supplement along with standard care against standard care alone over six days.
The results revealed that incorporating the supplement with standard care led to notable improvements in certain symptoms associated with sore throat, such as throat pain and swallowing difficulties by day four and six. Although zinc was part of the blend, it was challenging to pinpoint its independent effect, given that it was studied alongside honey and propolis.
Interestingly, only one child in the standard care group needed additional medications like ibuprofen, highlighting that the supplement may reduce the need for further treatment. Importantly, we did not report any adverse events, making this combination a potential safe addition to treatment.
Overall, while the study presents encouraging results regarding the adjunctive use of the supplement in treating sore throat, it remains unclear how much zinc alone contributes to its effectiveness.
7
Zinc's role in sore throat relief
The Effects of a Dietary Supplement (PediaFlù) Plus Standard of Care in Children With Acute Tonsillopharyngitis/Rhinopharyngitis: Protocol for a Randomized Controlled Trial.
We targeted the effectiveness of a dietary supplement that includes zinc, among other ingredients, in treating acute tonsillopharyngitis and rhinopharyngitis in children. This trial was carefully designed to compare the supplement combined with standard care against standard care alone.
Our focus was on children aged 3 to 10 years suffering from sore throat symptoms. We employed a randomized, controlled setup, ensuring a solid methodological foundation for our findings. The primary goals included assessing severity of throat pain and the necessity for additional rescue medications.
The results highlighted the supplement's potential as an add-on treatment. While it shows promise in alleviating symptoms, we must note that we cannot isolate zinc's effects from other components like Pelargonium sidoides and propolis.
Ultimately, these insights could guide future treatments where antibiotics are avoided, especially when there's no streptococcal infection involved.
9.5
Zinc reduces postoperative sore throat
Preoperative oral zinc tablet decreases incidence of postoperative sore throat.
We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
9
Zinc reduces postoperative sore throat
The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study.
We explored the potential benefits of zinc lozenges for easing postoperative sore throat (POST), a common discomfort following endotracheal intubation. By conducting a randomized, double-blinded trial with 79 patients undergoing low- to moderate-risk surgeries, we divided participants into two groups: one received zinc lozenges, while the other was given a placebo.
Our findings revealed promising results. At the crucial four-hour mark post-surgery, only 7% of patients who took zinc experienced POST, compared to 29% in the placebo group. Interestingly, the difference was even more pronounced right after surgery, where the zinc group reported a 0% incidence of POST versus 24% for the control group.
Moreover, the severity of sore throat symptoms was notably less intense among those in the zinc group. Those with mild and moderate sore throat pains reported significantly lower severity scores. These results suggest that a single dose of 40 mg of zinc lozenges taken just 30 minutes before surgery can greatly aid in reducing both the occurrence and discomfort of POST in the early hours after surgery.
References
Cardinale F, Barattini DF, Martinucci V, Bordea MM, Barattini L, et al. The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial. Pharmaceuticals (Basel). 2024;17. doi:10.3390/ph17060804
Cardinale F, Barattini DF, Sbrocca F, Centi A, Giuntini G, et al. The Effects of a Dietary Supplement (PediaFlù) Plus Standard of Care in Children With Acute Tonsillopharyngitis/Rhinopharyngitis: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2024;13:e53703. doi:10.2196/53703
Bhanwra A, Palta S, Saroa R, Saxena P, Bhanwra S, et al. Role of preoperative zinc, magnesium and budesonide gargles in Postoperative Sore Throat (POST) - a randomised control trial. BMC Anesthesiol. 2024;24:164. doi:10.1186/s12871-024-02534-5
Mondal AK, Maiti AK, Chattopadhyay S, Bhar D. A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation. Indian J Anaesth. 2023;67:S261. doi:10.4103/ija.ija_975_22
Sarkar T, Mandal T. Preoperative oral zinc tablet decreases incidence of postoperative sore throat. Indian J Anaesth. 2020;64:409. doi:10.4103/ija.IJA_959_19
Thomsen M, Vitetta L. Zinc deficits, mucositis, and mucosal macrophage perturbation: is there a relationship?. Curr Opin Clin Nutr Metab Care. 2019;22:365. doi:10.1097/MCO.0000000000000588
Farhang B, Grondin L. The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study. Anesth Analg. 2018;126:78. doi:10.1213/ANE.0000000000002494
Sun GB, Sun N, Tang HH, Zhu QB, Wen W, et al. Zinc sulfate therapy of vocal process granuloma. Eur Arch Otorhinolaryngol. 2012;269:2087. doi:10.1007/s00405-012-1971-1
Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PH. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2000;133:245.